2017

Medina-Rodríguez EM*, Bribián A*, Boyd A, Pastor J, Lagares A, Gil C, Martínez A, Williams A, & de Castro F (2017) New small phosphodiesterase 7 blockers effectively promote remyelination in vivo and open new neuroreparative strategies for clinical use in Multiple Sclerosis. Sci. Rep. 7, 43545 (doi: 10.1038/srep43545).

Leonetti C, Macrez R, Pruvost M, Bronsard J, Fournier A, Perrigault M, Vivien D, Clemente D, de Castro F, Maubert E*, & Docagne F* (2017) Tissue plasminogen activator exerts chemokinetic effects on oligodendrocytes in white matter (re)myelination. Molecular Neurodegeneration 12:20 (DOI: 10.1186/s13024-017-0160-5).

Pintado-Sierra, M., García-Álvarez, I., Bribián, A., Medina-Rodríguez, E.M., Lebrón-Aguilar, R., Garrido, L., de Castro, F., Fernández-Mayoralas, A., & Quintanilla-López, J.E. (2017) A comprehensive profiling of sulfatides in myelin from mouse brain using liquid chromatography-tandem mass spectrometry and high resolution accurate mass spectrometry. Analyt. Chim. Acta 951, 89-98.

   Marín-Bañasco, C., Benabdellah, K., Melero-Jerez, C., Oliver, B., Pinto-Medel, M.J., Hurtado-Guerrero, I., de Castro, F., Clemente, D., Fernández, Ó., Martin, F., Leyva, L., & Suardíaz-García, M. (2017) Gene therapy with mesenchymal stem cells expressing IFNß ameliorates neuroinflammation in experimental models of Multiple Sclerosis. Br. J. Pharmacol. 174, 238-253 (doi: 10.1111/bph.13674).

de Castro, F. (2017) Human adult Oligodendrocyte Precursor Cell biology: the bottleneck for effective pro-remyelinating therapies for Multiple Sclerosis. In: Converging Clinical and Engineering Research on Neurorehabilitation (Editors: J.L. Pons & XXX) Springer International Publishing. Vol. II, 67-68.


2016
        
            de Castro, F., Seal, R., y Maggi, R. (2016) ANOS1: a unified nomenclature for Kallmann syndrome 1 gene (KAL1) and anosmin-1. Brief. Funct. Genom. (In Press, BFGP-16-0031).   
            de Castro, F., & Merchán, M.A. (2016) Editorial: The major discoveries of Cajal and his disciples: Consolidated milestones for the Neuroscience of the XXIst century. Front. Neuroanat. 10:85 (doi: 10.3389/fnana.2016.00085).

Suardíaz, M., Clemente, D., Marín-Bañasco, C., Orpez, T., Guerrero-Hurtado, I., Pavía, P., Pinto-Medel, M.J., de Castro, F., Leyva, L., Fernández, Ó, & Oliver, B. (2016) Recombinant soluble IFN receptor (sIFNAR2) exhibits intrinsic therapeutic efficacy in a murine model of Multiple Sclerosis. Neuropharmacology 110, 480-492. (doi: 10.1016/j.neuropharm.2016.07.026).

Sierra A, de Castro F, del Río-Hortega J, Iglesias-Rozas J, Garrosa M, & Kettenmann H (2016) The `big-bang´ for modern glial biology: translation and comments on Pío del Río-Hortega 1919 series of papers on microglia.  Glia, 64:1801–1840 (doi:10.1002/glia.23046). “Cover page” selected for Volume 64 (Issue 11, pages 1795–2040). Recommended in F1000Prime as being of special significance in its field (http://f1000.com/prime/726748849?bd=1).

Macrez*, R., Ortega*, M.C., Bardou, I., Mehra, A., Fournier, A., Van der Pol, S.M.A., Haelewyn, B., Maubert, E., Lesept, F., Chevilley, A., de Castro, F., De Vries, H.E., Vivien, D., Clemente*, D., & Docagne*, F. (2016) Neuroendothelial NMDA receptors as therapeutic targets in experimental autoimmune encephalomyelitis. Brain 139; 2406–2419 (doi: http://dx.doi.org/10.1093/brain/aww172).

de Castro, F. (2016) The Cajal School in the peripheral nervous system: the transcendent contributions of Fernando de Castro on the microscopic structure of sensory and autonomic motor ganglia. Front. Neuroanat. 10:43 (1-11) (doi: 10.3389/fnana.2016.00043).

de Castro, F., & López-Mascaraque, L. (2016) Olfactory system embryonic development. In: Kaufman’s Atlas of Mouse Development Supplement: With Coronal Sections (ISBN: 978-0-12-800043-4; editors: R. Baldock, J. Bard, D.C. Davidson & G. Morriss-Kay). Pp. 286-292. Academic Press-Elsevier, USA/UK (doi: http://dx.doi.org/10.1016/B978-0-12-800043-4.00022-1).

García-González, D., Murcia-Belmonte, M., Esteban, P.F., Ortega, F., Díaz, D., Sánchez-Vera, I., Lebrón-Galán, R., Escobar-Castañondo, L., Martínez-Millán, L., Weruaga, E., García-Verdugo, J.M., Berninger, B., & de Castro, F. (2016) Anosmin-1 over-expression increases adult neurogenesis in the subventricular zone and neuroblast migration to the olfactory bulb. Brain Struct. Funct. 221(1):239–260. (doi 10.1007/s00429-014-0904-8; PMID: 25300351).

Murcia-Belmonte V., Esteban P.F., Martínez-Hernández J., Gruart A., Luján R., Delgado-García J.M., & de Castro F. (2016) Anosmin-1 over-expression regulates oligodendrocyte precursor cell proliferation, migration and myelin sheath thickness. Brain Struc. Funct. 221, 1365-1385 (doi 10.1007/s00429-014-0977-4; PMID: 25662897).

Moliné-Velázquez, V., Vila-del Sol, V., de Castro, F., & Clemente, D. (2016) Myeloid cell distribution and activity in mutiple sclerosis. Histol. Histopathol. 31, 357-370 (DOI: 10.14670/HH-11-699).

Merchán, M.A., DeFelipe, J., & de Castro, F. editores (2016) “Cajal and De Castro´s Neurohistological Methods”. Oxford University Press, Oxford (Gran Bretaña). ISBN 978-0-19-022159-1, 252 pages.

Gutiérrez-Franco, A., Costa, C., Eixarch, H., Castillo, M., Medina-Rodríguez, E.M., Bribián, A., de Castro, F., Montalbán, X., & Espejo, C. (2016) Differential expression of sema3A and sema7A in a murine model of multiple sclerosis: implications for a therapeutic design. Clin. Immunol. 163, 22–33 (doi:10.1016/j.clim.2015.12.005).

Murcia-Belmonte V., Esteban P.F., Martínez-Hernández J., Gruart A., Luján R., Delgado-García J.M., & de Castro F. (2016) Anosmin-1 over-expression regulates oligodendrocyte precursor cell proliferation, migration and myelin sheath thickness. Brain Struc. Funct. 221, 1365-1385 (doi 10.1007/s00429-014-0977-4; PMID: 25662897).

García-González, D., Murcia-Belmonte, M., Esteban, P.F., Ortega, F., Díaz, D., Sánchez-Vera, I., Lebrón-Galán, R., Escobar-Castañondo, L., Martínez-Millán, L., Weruaga, E., García-Verdugo, J.M., Berninger, B., & de Castro, F. (2016) Anosmin-1 over-expression increases adult neurogenesis in the subventricular zone and neuroblast migration to the olfactory bulb. Brain Struct. Funct. 221(1):239–260. (doi 10.1007/s00429-014-0904-8; PMID: 25300351).



2015

    Cases, O., Joseph, A., Obry, A., Santin, M.D., Pâques, M., Ben-Yacoub, S., Amsellem, S., Bribián, A., Simonutti, M., Augustin, S., Debeir, T., Sahel, J.-A., Christ, A., de Castro, F., Lehéricy, S., Cosette, P., and Kozyraki, R. (2015). Foxg1-cre mediated Lrp2 inactivation in the developing mouse neural retina, ciliary and retinal pigment epithelia models congenital high myopia. PLOS ONE In Press (PONE-D-14-55738R2).


2014


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Polo-Hernández, E., Tello, V., Arroyo, A.A., Domínguez-Prieto, M., de Castro, F., Tabernero, A., & Medina, J.M. (2014) Oleic acid synthesized by stearoyl-CoA desaturase (SCD-1) in the lateral periventricular zone of the developing rat brain mediates neuronal growth, migration and the arrangement of prospective synapses. Brain Res. 1570, 13-25 (doi 10.1016/j.brainres.2014.04.038). 

 
        Moliné-Velázquez, V., Ortega, M.C., Vila del Sol, V., Melero-Jerez, C., de Castro, F., & Clemente, D. (2014) The synthetic retinoid Am80 delays recovery in a model of multiple sclerosis by modulating myeloid-derived suppressor cell fate and viability. Neurobiol. Dis. 67, 149–164 (doi 10.1016/j.nbd.2014.03.017).   
         Bello-Morales, R., Crespillo, A.J., García, B., Dorado, L.A., Martín, B., Tabarés, E., Krummenacher, C., de Castro, F., and López-Guerrero, J.A. (2014) The effect of cellular differentiation on HSV-1 infection of oligodendrocytic cells. PLOS ONE 9(2):e89141 (doi: 10.1371/journal.pone.0089141).
          de Castro, F., Esteban, P.F., Bribián, A., Murcia-Belmonte, V., García-González, D., & Clemente, D. (2014) The adhesion molecule Anosmin-1 in Neurology: Kallmann syndrome and beyond. In: "Advances in Neurobiology Series- Cell Adhesion Molecules: Implications in Neurological Diseases" (eds.: Schledermann, P., and Berezin, V.). Springer (Alemania). Adv. Neurobiol. 8, 273-292.

2013

Clemente*, D., Ortega, M.,C., Melero-Jerez, C., & de Castro*, F. (2013) The effect of glia-glia interactions on oligodendrocyte precursor cell biology during development and in demyelinating diseases Front. Cell Neurosci. 7, 268 (1-15) doi: 10.3389/fncel.2013.00268.

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Murcia-Belmonte, V., Medina-Rodríguez, E.M., Bribián, A., de Castro*, F., & Esteban*, P.F. (2013) ERK1/2 signalling is essential for the chemoattraction exerted by human FGF2 and human anosmin-1 on newborn rat and mouse OPCs via FGFR1. Glia 62, 374-386 (doi: 10.1002/glia.22609).

 
         Medina-Rodríguez, E.M., Arenzana, F.J., Bribián, A., & de Castro, F. (2013) Protocol to isolate a large amount of functional oligodendrocyte precursor cells from the cerebral cortex of adult mice and humans. PLOS ONE 8 (11): e81620 (doi:10.1371/journal.pone).          
         de Castro, F., Bribián, A., & Ortega, M.C. (2013) Regulation of oligodendrocyte precursor migration during development, in adulthood and in pathology. Cell. Mol. Life Sci. 70, 4355-4368 (DOI: 10.1007/s00018-013-1365-6). 
         Velasco, S., & de Castro, F. (2013) Anosmin-1 and galectin-1 as laminin interactors in nervous system development and pathology. In: "Laminins: Structure, Biological Activity and Role in Disease" (ed. H.M. Mora-Montes; ISBN 978-1-62618568-5), Nova Science Publishers Inc., New York (USA).  Ch. 3, Pp. 53-68. 
         Medina-Rodríguez E.M., Arenzana F.J., Pastor J., Redondo M., Palomo V., García de Sola R., Gil C., Martínez A., Bribián* A., y de Castro* F. (2013) Inhibition of endogenous phosphodiesterase 7 promotes oligodendrocyte precursor differentiation and survival.  Cell. Mol. Life Sci.  70, 3449-3462. (DOI: 10.1007/s00018-013-1340-2). 
         García-González, D., Murcia-Belmonte, V., Clemente, D., and de Castro, F. (2013) Olfactory system and demyelination. Anat. Rec. 296, 1424-1434.  Selected “Cover page” for volume 296, number 9. 
         de Castro, F., and Zalc, B. (2013) Migration of myelin-forming cells in the CNS. In"Comprehensive Developmental Neuroscience: Cellular Migration and Formation of Neuronal Connections" (editors: Rakic, P., and Rubenstein, J.) Vol. 2, pp. 417-429, Elsevier (Holland). 
          Esteban P.F.*, Murcia-Belmonte V.*, García-González D. & de Castro F. (2013) The cysteine-rich region and the whey acidic protein domain are essential for anosmin-1 biological functions. J. Neurochem. 124, 708-720. doi: 10.1111/jnc.12104. 

2012

Suárez, R.*, García-González, D.*, y de Castro, F. (2012) Mutual influences between the main olfactory and vomeronasal systems in development and evolution. Front. Neuroanat. 6:50. (doi: 10.3389/fnana.2012.00050).

 pdf (linked)

Ortega*, M.C., Bribián*, A., Peregrin, S., Gil, T., Marín#, O., & de Castro#, F. (2012) Neuregulin-1/ErbB4 signaling controls the migration of oligodendrocyte precursor cells during development. Exp. Neurol. 235, 610-620 (DOI 10.1016/j.expneurol.2012.03.015)

 

           Bribián, A., Fontana, X., Llorens, F., Gavín, R., Reina, M., García-Verdugo, J.M., Torres, J.M., de Castro, F., & del Río, J.A. (2012) Role of the cellular prion protein in oligodendrocyte precursor cell proliferation and differentiation in the developing and adult mouse CNS. PLoS ONE 7(4):e33872.        

 

            Ortega, M.C., Cases, O., Merchán, P., Kozyraki, R., Clemente, D., & de Castro, F. (2012) Megalin mediates the influence of Sonic Hedgehog on oligodendrocyte precursor cell migration and proliferation during development. Glia 60, 851-66 (doi: 10.1002/glia.22316).        

 

 Moreno, B., Espejo, C., Mestre, L., Suardíaz, M., Clemente, D., de Castro, F., Fernández, O., Montalbán, X., Villoslada, P., and Guaza, C. (2012) Guías para el uso adecuado de modelos animales para el desarrollo de terapias en esclerosis múltiple. Rev. Neurol. 54, 114-124.

 
             García-Armendáriz*, B., Bribián*, A., Pérez-Martínez, E., Martínez, A., de Castro, F., Soriano, E., & Burgaya, F. (2012) Expression of Semaphorin 4F in neurons and brain oligodendrocytes and the regulation of oligodendrocyte precursor migration in the optic nerve. Mol. Cell. Neurosci. 49, 54-67 (doi:10.1016/j.mcn.2011.09.003). 

2011

            Coveñas, R., Mangas, A., Duleu, S., de Castro, F.,  Merchán, M., and Geffard, M. (2011) Immunopathology and immunomodulation in experimental autoimmune encaphalomyelitis and Multiple Sclerosis. In: "Multiple Sclerosis: A New Paradigm", editor Geffard, M. (ISBN: 978-1-61122-642-3). Nova Science Publishers, New York (USA), pp. 69-131. 

 pdf (linked)

            Clemente, D., Ortega, M.C., Arenzana, F.J., and de Castro, F. (2011) FGF-2 and Anosmin-1 are selectively expressed in different types of multiple sclerosis lesions. J. Neurosci. 31, 14899-14909 (doi: 10.1523/​JNEUROSCI.1158-11.2011).

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            Moliné-Velázquez, V., Cuervo, H., Vila del Sol, V., Ortega, M.C., Clemente, D., & de Castro, F. (2011) Myeloid-derived suppressor cells limit the inflammation by promoting T lymphocyte apoptosis in the spinal cord of a murine model of multiple sclerosis. Brain Pathol. 21, 678-691 (doi:10.1111/j.1750-3639.2011.00495.x). "Cover page" selected for volume 21.

 

García-González, D., & de Castro, F. (2011) How is the sense of smell connected? Cellular and molecular mechanism guiding the development of the synaptic connections from the nose to the cortex (II). Rev. Neurol. 52, 548-554.    

 

García-González D, & de Castro, F. (2011) How is the sense of smell connected? Cellular and molecular mechanism guiding the development of the synaptic connections from the nose to the cortex (I). Rev Neurol. 52, 477-488.

 

2010

de Castro, F. (2010) Regeneración en esclerosis Múltiple. In: "Tratado de esclerosis múltiple" (editor:  Villoslada, P.). Editorial Marge Médica Books (Spain).

 

Murcia-Belmonte, V., Esteban, P.F., García-González, D., & de Castro, F. (2010) Biochemical dissection of Anosmin-1 interaction with FGFR1 and other components of the extracellular matrix. J. Neurochem. 115, 1256-1265 DOI:10.1111/j.1471-4159.2010.07024.

 

Vitureira, N., Andres, R., Perez, E., Martínez, A., Bribián, A., Blasi, J., Chelliah, S., López, G., de Castro, F., Burgaya, F., McNagny, K.M., and Soriano, E. (2010) Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation. PLoS ONE 5(8), pii: e12003.

 

Polo-Hernández, E., de Castro, F., García-García, A., Tabernero, A. and Medina, J.M. (2010) Oleic acid synthesized in the periventricular zone promotes axonogenesis in the striatum during brain development. J. Neurochem. 114, 1756-1766 (doi: 10.1111/j.1471-4159.2010.06891.x).

 

García-González, D., Clemente, D., Coelho, M., Esteban, P., Soussi-Yanicostas, N., & de Castro, F. (2010) Dynamic roles of FGF-2 and Anosmin-1 in the migration of neuronal precursors from the subventricular zone during pre- and postnatal development. Exp. Neurol. 222, 285–295 (doi:10.1016/j.expneurol.2010.01.006). “Cover page” number 2, volume 222.

 

2009
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